Compile Data Set for Download or QSAR

Found 1026 hits of ic50 data for polymerid = 49000307,49000311,50000702,50002642,50006869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487585 (CHEMBL2237954) Show SMILES CCc1nc(C2C(C(=O)OC)=C(C)NC(C)=C2C(=O)OCCc2ccccc2)c(Cl)[nH]1 |c:15,t:10| Show InChI InChI=1S/C23H26ClN3O4/c1-5-16-26-20(21(24)27-16)19-17(22(28)30-4)13(2)25-14(3)18(19)23(29)31-12-11-15-9-7-6-8-10-15/h6-10,19,25H,5,11-12H2,1-4H3,(H,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.0309	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487598 (CHEMBL2237953) Show SMILES CCc1nc(C2C(C(=O)OCCc3ccccc3)=C(C)NC(C)=C2C(=O)OCCc2ccccc2)c(Cl)[nH]1 |c:23,t:18| Show InChI InChI=1S/C30H32ClN3O4/c1-4-23-33-27(28(31)34-23)26-24(29(35)37-17-15-21-11-7-5-8-12-21)19(2)32-20(3)25(26)30(36)38-18-16-22-13-9-6-10-14-22/h5-14,26,32H,4,15-18H2,1-3H3,(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.0437	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487582 (CHEMBL2237955) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1nc(CC)[nH]c1Cl)C(=O)OCCc1ccccc1 |c:5,10| Show InChI InChI=1S/C24H28ClN3O4/c1-5-17-27-21(22(25)28-17)20-18(23(29)31-6-2)14(3)26-15(4)19(20)24(30)32-13-12-16-10-8-7-9-11-16/h7-11,20,26H,5-6,12-13H2,1-4H3,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.0457	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487589 (CHEMBL2261189) Show SMILES CCc1nc(Cl)c([nH]1)C1C(C(=O)OCCCc2ccccc2)=C(C)NC(C)=C1C(=O)OCCCc1ccccc1 |c:28,t:23| Show InChI InChI=1S/C32H36ClN3O4/c1-4-25-35-29(30(33)36-25)28-26(31(37)39-19-11-17-23-13-7-5-8-14-23)21(2)34-22(3)27(28)32(38)40-20-12-18-24-15-9-6-10-16-24/h5-10,13-16,28,34H,4,11-12,17-20H2,1-3H3,(H,35,36)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.0668	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487592 (CHEMBL2261183) Show SMILES CCCOC(=O)C1=C(C)NC(C)=C(C1c1[nH]c(CC)nc1Cl)C(=O)OCCC |c:6,11| Show InChI InChI=1S/C20H28ClN3O4/c1-6-9-27-19(25)14-11(4)22-12(5)15(20(26)28-10-7-2)16(14)17-18(21)24-13(8-3)23-17/h16,22H,6-10H2,1-5H3,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487590 (CHEMBL2261188) Show SMILES CCc1nc(Cl)c([nH]1)C1C(C(=O)OC2CCCCC2)=C(C)NC(C)=C1C(=O)OC1CCCCC1 |c:25,t:20| Show InChI InChI=1S/C26H36ClN3O4/c1-4-19-29-23(24(27)30-19)22-20(25(31)33-17-11-7-5-8-12-17)15(2)28-16(3)21(22)26(32)34-18-13-9-6-10-14-18/h17-18,22,28H,4-14H2,1-3H3,(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.132	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487588 (CHEMBL2261191) Show SMILES CCCOC(=O)C1=C(C)NC(C)=C(C1c1[nH]c(CC)nc1Cl)C(=O)OC |c:6,11| Show InChI InChI=1S/C18H24ClN3O4/c1-6-8-26-18(24)13-10(4)20-9(3)12(17(23)25-5)14(13)15-16(19)22-11(7-2)21-15/h14,20H,6-8H2,1-5H3,(H,21,22)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.146	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487593 (CHEMBL2261182) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1[nH]c(CC)nc1Cl)C(=O)OCC |c:5,10| Show InChI InChI=1S/C18H24ClN3O4/c1-6-11-21-15(16(19)22-11)14-12(17(23)25-7-2)9(4)20-10(5)13(14)18(24)26-8-3/h14,20H,6-8H2,1-5H3,(H,21,22)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.158	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486421 (CHEMBL2237950) Show SMILES CC1=C(C(c2nc[nH]c2Cl)C(C(=O)OCCc2ccccc2)=C(C)N1)C(=O)OCCc1ccccc1 |t:1,23| Show InChI InChI=1S/C28H28ClN3O4/c1-18-22(27(33)35-15-13-20-9-5-3-6-10-20)24(25-26(29)31-17-30-25)23(19(2)32-18)28(34)36-16-14-21-11-7-4-8-12-21/h3-12,17,24,32H,13-16H2,1-2H3,(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.182	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of L-type calcium channel in Cavia porcellus (guinea pig) ileal SMC assessed as inhibition of 80 mM KCl-induced current				Citation and Details Article DOI: 10.1007/s00044-010-9515-y BindingDB Entry DOI: 10.7270/Q2W098T5
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487591 (CHEMBL2261187) Show SMILES CCc1nc(Cl)c([nH]1)C1C(C(=O)OC2CCCC2)=C(C)NC(C)=C1C(=O)OC1CCCC1 |c:24,t:19| Show InChI InChI=1S/C24H32ClN3O4/c1-4-17-27-21(22(25)28-17)20-18(23(29)31-15-9-5-6-10-15)13(2)26-14(3)19(20)24(30)32-16-11-7-8-12-16/h15-16,20,26H,4-12H2,1-3H3,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.212	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487587 (CHEMBL2261192) Show SMILES CCc1nc(Cl)c([nH]1)C1C(C(=O)OC)=C(C)NC(C)=C1C(=O)OC(C)C |c:19,t:14| Show InChI InChI=1S/C18H24ClN3O4/c1-7-11-21-15(16(19)22-11)14-12(17(23)25-6)9(4)20-10(5)13(14)18(24)26-8(2)3/h8,14,20H,7H2,1-6H3,(H,21,22)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.488	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487595 (CHEMBL2261195) Show SMILES CCCOC(=O)C1=C(C)NC(C)=C(C1c1[nH]c(CC)nc1Cl)C(=O)OCC |c:6,11| Show InChI InChI=1S/C19H26ClN3O4/c1-6-9-27-19(25)14-11(5)21-10(4)13(18(24)26-8-3)15(14)16-17(20)23-12(7-2)22-16/h15,21H,6-9H2,1-5H3,(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.543	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487600 (CHEMBL2261196) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1[nH]c(CC)nc1Cl)C(=O)OC(C)C |c:5,10| Show InChI InChI=1S/C19H26ClN3O4/c1-7-12-22-16(17(20)23-12)15-13(18(24)26-8-2)10(5)21-11(6)14(15)19(25)27-9(3)4/h9,15,21H,7-8H2,1-6H3,(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.564	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487594 (CHEMBL2261181) Show SMILES CCc1nc(Cl)c([nH]1)C1C(C(=O)OC)=C(C)NC(C)=C1C(=O)OC |c:19,t:14| Show InChI InChI=1S/C16H20ClN3O4/c1-6-9-19-13(14(17)20-9)12-10(15(21)23-4)7(2)18-8(3)11(12)16(22)24-5/h12,18H,6H2,1-5H3,(H,19,20)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.596	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487599 (CHEMBL2261184) Show SMILES CCc1nc(Cl)c([nH]1)C1C(C(=O)OC(C)C)=C(C)NC(C)=C1C(=O)OC(C)C |c:21,t:16| Show InChI InChI=1S/C20H28ClN3O4/c1-8-13-23-17(18(21)24-13)16-14(19(25)27-9(2)3)11(6)22-12(7)15(16)20(26)28-10(4)5/h9-10,16,22H,8H2,1-7H3,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.748	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487580 (CHEMBL2237952) Show SMILES CCc1nc(C2C(C(=O)OCc3ccccc3)=C(C)NC(C)=C2C(=O)OCc2ccccc2)c(Cl)[nH]1 |c:22,t:17| Show InChI InChI=1S/C28H28ClN3O4/c1-4-21-31-25(26(29)32-21)24-22(27(33)35-15-19-11-7-5-8-12-19)17(2)30-18(3)23(24)28(34)36-16-20-13-9-6-10-14-20/h5-14,24,30H,4,15-16H2,1-3H3,(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.906	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Oryctolagus cuniculus)	BDBM50227241 (CHEMBL1202817) Show SMILES Cl.CCCCN(CCCC)CCCOc1ccc(cc1)-c1cn2ccc(C)nc2n1 Show InChI InChI=1S/C24H34N4O/c1-4-6-14-27(15-7-5-2)16-8-18-29-22-11-9-21(10-12-22)23-19-28-17-13-20(3)25-24(28)26-23/h9-13,17,19H,4-8,14-16,18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Ortho Pharmaceutical Corporation Curated by ChEMBL					Assay Description Inhibition of [3H]nitrendipine binding to calcium channels in Rabbit cardiac muscle.				J Med Chem 31: 2221-7 (1988) BindingDB Entry DOI: 10.7270/Q2T72J19
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Oryctolagus cuniculus)	BDBM50336640 ((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1[N+]([O-])=O |c:13,t:10| Show InChI InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,13,15H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Ortho Pharmaceutical Corporation Curated by ChEMBL					Assay Description Inhibition of [3H]nitrendipine binding to calcium channels in Rabbit cardiac muscle.				J Med Chem 31: 2221-7 (1988) BindingDB Entry DOI: 10.7270/Q2T72J19
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487601 (CHEMBL2261198) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1[nH]c(CC)nc1Cl)C(=O)OCC1CCCCC1 |c:5,10| Show InChI InChI=1S/C23H32ClN3O4/c1-5-16-26-20(21(24)27-16)19-17(22(28)30-6-2)13(3)25-14(4)18(19)23(29)31-12-15-10-8-7-9-11-15/h15,19,25H,5-12H2,1-4H3,(H,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50336640 ((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1[N+]([O-])=O |c:13,t:10| Show InChI InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,13,15H,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of rat Cav1.2 channel in rat mesenteric artery assessed as relaxation of 70 mM K+ induced contraction				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Oryctolagus cuniculus)	BDBM50002644 (2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-dihydro-pyridi...) Show SMILES CC(C)OC(=[OH+])C1=C(C)N=C(C)C(C1c1ccccc1[N+]([O-])=O)=C([O-])OCN1C(=O)c2ccccc2S1(=O)=O |w:23.25,c:6,t:9| Show InChI InChI=1S/C26H25N3O9S/c1-14(2)38-26(32)22-16(4)27-15(3)21(23(22)17-9-5-7-11-19(17)29(33)34)25(31)37-13-28-24(30)18-10-6-8-12-20(18)39(28,35)36/h5-12,14,23,31H,13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Alter, S.A. Curated by ChEMBL					Assay Description Blockade of calcium-evoked contractions in depolarized aortic strips				J Med Chem 35: 2407-14 (1992) BindingDB Entry DOI: 10.7270/Q2BV7H7B
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486778 (CHEMBL2236229) Show SMILES CSc1ncc(C2C(C(=O)OCc3ccccc3)=C(C)NC(C)=C2C(=O)OCc2ccccc2)n1Nc1ccccc1 |c:23,t:18| Show InChI InChI=1S/C33H32N4O4S/c1-22-28(31(38)40-20-24-13-7-4-8-14-24)30(27-19-34-33(42-3)37(27)36-26-17-11-6-12-18-26)29(23(2)35-22)32(39)41-21-25-15-9-5-10-16-25/h4-19,30,35-36H,20-21H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	1.49	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486800 (CHEMBL2236232) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1cnc(SC)n1Nc1ccccc1)C(=O)OC |c:5,10| Show InChI InChI=1S/C22H26N4O4S/c1-6-30-21(28)18-14(3)24-13(2)17(20(27)29-4)19(18)16-12-23-22(31-5)26(16)25-15-10-8-7-9-11-15/h7-12,19,24-25H,6H2,1-5H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	1.66	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486789 (CHEMBL2236225) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1cnc(SC)n1Nc1ccccc1)C(=O)OCC |c:5,10| Show InChI InChI=1S/C23H28N4O4S/c1-6-30-21(28)18-14(3)25-15(4)19(22(29)31-7-2)20(18)17-13-24-23(32-5)27(17)26-16-11-9-8-10-12-16/h8-13,20,25-26H,6-7H2,1-5H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	1.69	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487586 (CHEMBL2261194) Show SMILES CCc1nc(Cl)c([nH]1)C1C(C(=O)OC)=C(C)NC(C)=C1C(=O)OCc1ccccc1 |c:19,t:14| Show InChI InChI=1S/C22H24ClN3O4/c1-5-15-25-19(20(23)26-15)18-16(21(27)29-4)12(2)24-13(3)17(18)22(28)30-11-14-9-7-6-8-10-14/h6-10,18,24H,5,11H2,1-4H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486433 (CHEMBL2237951) Show SMILES CC1=C(C(c2nc[nH]c2Cl)C(C(=O)OCCCc2ccccc2)=C(C)N1)C(=O)OCCCc1ccccc1 |t:1,24| Show InChI InChI=1S/C30H32ClN3O4/c1-20-24(29(35)37-17-9-15-22-11-5-3-6-12-22)26(27-28(31)33-19-32-27)25(21(2)34-20)30(36)38-18-10-16-23-13-7-4-8-14-23/h3-8,11-14,19,26,34H,9-10,15-18H2,1-2H3,(H,32,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of L-type calcium channel in Cavia porcellus (guinea pig) ileal SMC assessed as inhibition of 80 mM KCl-induced current				Citation and Details Article DOI: 10.1007/s00044-010-9515-y BindingDB Entry DOI: 10.7270/Q2W098T5
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486798 (CHEMBL2236212) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1cnc(SC)n1Nc1ccccc1)C(=O)OCc1ccccc1 |c:5,10| Show InChI InChI=1S/C28H30N4O4S/c1-5-35-26(33)23-18(2)30-19(3)24(27(34)36-17-20-12-8-6-9-13-20)25(23)22-16-29-28(37-4)32(22)31-21-14-10-7-11-15-21/h6-16,25,30-31H,5,17H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	1.86	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487581 (CHEMBL2261190) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1[nH]c(CC)nc1Cl)C(=O)OC |c:5,10| Show InChI InChI=1S/C17H22ClN3O4/c1-6-10-20-14(15(18)21-10)13-11(16(22)24-5)8(3)19-9(4)12(13)17(23)25-7-2/h13,19H,6-7H2,1-5H3,(H,20,21)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486803 (CHEMBL2236227) Show SMILES CSc1ncc(C2C(C(=O)OC(C)C)=C(C)NC(C)=C2C(=O)OC(C)C)n1Nc1ccccc1 |c:18,t:13| Show InChI InChI=1S/C25H32N4O4S/c1-14(2)32-23(30)20-16(5)27-17(6)21(24(31)33-15(3)4)22(20)19-13-26-25(34-7)29(19)28-18-11-9-8-10-12-18/h8-15,22,27-28H,1-7H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	2.16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM50436176 (Dynacirc | Dynacirc Cr | ISRADIPINE | Isrodipine |...) Show SMILES COC(=O)C1=C(C)NC(C)=C(C1c1cccc2nonc12)C(=O)OC(C)C |c:4,9| Show InChI InChI=1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel measured using 2-electrode voltage-clamp in human embryonic kidney cells heterologically expressing alpha-1C sub...				J Appl Toxicol 32: 858-66 (2012) Article DOI: 10.1002/jat.2784 BindingDB Entry DOI: 10.7270/Q2D79D5C
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486799 (CHEMBL2236236) Show SMILES COC(=O)C1=C(C)NC(C)=C(C1c1cnc(SC)n1Nc1ccccc1)C(=O)OCc1ccccc1 |c:4,9| Show InChI InChI=1S/C27H28N4O4S/c1-17-22(25(32)34-3)24(21-15-28-27(36-4)31(21)30-20-13-9-6-10-14-20)23(18(2)29-17)26(33)35-16-19-11-7-5-8-12-19/h5-15,24,29-30H,16H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	2.21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486801 (CHEMBL2236226) Show SMILES CCCOC(=O)C1=C(C)NC(C)=C(C1c1cnc(SC)n1Nc1ccccc1)C(=O)OCCC |c:6,11| Show InChI InChI=1S/C25H32N4O4S/c1-6-13-32-23(30)20-16(3)27-17(4)21(24(31)33-14-7-2)22(20)19-15-26-25(34-5)29(19)28-18-11-9-8-10-12-18/h8-12,15,22,27-28H,6-7,13-14H2,1-5H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	2.29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486786 (CHEMBL2236233) Show SMILES CCCOC(=O)C1=C(C)NC(C)=C(C1c1cnc(SC)n1Nc1ccccc1)C(=O)OC |c:6,11| Show InChI InChI=1S/C23H28N4O4S/c1-6-12-31-22(29)19-15(3)25-14(2)18(21(28)30-4)20(19)17-13-24-23(32-5)27(17)26-16-10-8-7-9-11-16/h7-11,13,20,25-26H,6,12H2,1-5H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486781 (CHEMBL2236213) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1cnc(SC)n1Nc1ccccc1)C(=O)OCCCc1ccccc1 |c:5,10| Show InChI InChI=1S/C30H34N4O4S/c1-5-37-28(35)25-20(2)32-21(3)26(29(36)38-18-12-15-22-13-8-6-9-14-22)27(25)24-19-31-30(39-4)34(24)33-23-16-10-7-11-17-23/h6-11,13-14,16-17,19,27,32-33H,5,12,15,18H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	2.54	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487602 (CHEMBL2261185) Show SMILES CCc1nc(Cl)c([nH]1)C1C(C(=O)OCC(C)C)=C(C)NC(C)=C1C(=O)OCC(C)C |c:22,t:17| Show InChI InChI=1S/C22H32ClN3O4/c1-8-15-25-19(20(23)26-15)18-16(21(27)29-9-11(2)3)13(6)24-14(7)17(18)22(28)30-10-12(4)5/h11-12,18,24H,8-10H2,1-7H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50101817 (Adalat | Adalat Cc | Afeditab Cr | BAY-A-1040 | CH...) Show SMILES COC(=O)C1=C(C)NC(C)=C(C1c1ccccc1[N+]([O-])=O)C(=O)OC |c:4,9| Show InChI InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50487583 (CHEMBL2261199) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1[nH]c(CC)nc1Cl)C(=O)OCc1ccccc1 |c:5,10| Show InChI InChI=1S/C23H26ClN3O4/c1-5-16-26-20(21(24)27-16)19-17(22(28)30-6-2)13(3)25-14(4)18(19)23(29)31-12-15-10-8-7-9-11-15/h7-11,19,25H,5-6,12H2,1-4H3,(H,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of calcium channel in Cavia porcellus (guinea pig) ileum assessed as inhibition of KCl-induced contraction				Citation and Details Article DOI: 10.1007/s00044-009-9171-2 BindingDB Entry DOI: 10.7270/Q2WD43GV
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486787 (CHEMBL2236230) Show SMILES CSc1ncc(C2C(C(=O)OCCc3ccccc3)=C(C)NC(C)=C2C(=O)OCCc2ccccc2)n1Nc1ccccc1 |c:24,t:19| Show InChI InChI=1S/C35H36N4O4S/c1-24-30(33(40)42-21-19-26-13-7-4-8-14-26)32(29-23-36-35(44-3)39(29)38-28-17-11-6-12-18-28)31(25(2)37-24)34(41)43-22-20-27-15-9-5-10-16-27/h4-18,23,32,37-38H,19-22H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	2.79	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Oryctolagus cuniculus)	BDBM50336640 ((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1[N+]([O-])=O |c:13,t:10| Show InChI InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,13,15H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Alter, S.A. Curated by ChEMBL					Assay Description Blockade of calcium-evoked contractions in depolarized aortic strips				J Med Chem 35: 2407-14 (1992) BindingDB Entry DOI: 10.7270/Q2BV7H7B
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Oryctolagus cuniculus)	BDBM50002628 (4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-p...) Show SMILES COCCOC(=O)C1C(C(C(=O)OCN2C(=O)c3ccccc3S2(=O)=O)=C(C)N=C1C)c1cccc(Cl)c1Cl |c:30,t:27| Show InChI InChI=1S/C26H24Cl2N2O8S/c1-14-20(25(32)37-12-11-36-3)22(17-8-6-9-18(27)23(17)28)21(15(2)29-14)26(33)38-13-30-24(31)16-7-4-5-10-19(16)39(30,34)35/h4-10,20,22H,11-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Alter, S.A. Curated by ChEMBL					Assay Description Blockade of calcium-evoked contractions in depolarized aortic strips				J Med Chem 35: 2407-14 (1992) BindingDB Entry DOI: 10.7270/Q2BV7H7B
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486782 (CHEMBL2236211) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1cnc(SC)n1Nc1ccccc1)C(=O)OCCOC |c:5,10| Show InChI InChI=1S/C24H30N4O5S/c1-6-32-22(29)19-15(2)26-16(3)20(23(30)33-13-12-31-4)21(19)18-14-25-24(34-5)28(18)27-17-10-8-7-9-11-17/h7-11,14,21,26-27H,6,12-13H2,1-5H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	2.91	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM50101963 (BAY-K-5552 | CHEBI:76917 | Nisoldipine | Sular) Show SMILES COC(=O)C1=C(C)NC(C)=C(C1c1ccccc1[N+]([O-])=O)C(=O)OCC(C)C |c:4,9| Show InChI InChI=1S/C20H24N2O6/c1-11(2)10-28-20(24)17-13(4)21-12(3)16(19(23)27-5)18(17)14-8-6-7-9-15(14)22(25)26/h6-9,11,18,21H,10H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel measured using 2-electrode voltage-clamp in Chinese hamster ovary cells heterologically expressing alpha-1C subu...				J Appl Toxicol 32: 858-66 (2012) Article DOI: 10.1002/jat.2784 BindingDB Entry DOI: 10.7270/Q2D79D5C
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486777 (CHEMBL2236209) Show SMILES COC(=O)C1=C(C)NC(C)=C(C1c1cnc(SC)n1Nc1ccccc1)C(=O)OCCCc1ccccc1 |c:4,9| Show InChI InChI=1S/C29H32N4O4S/c1-19-24(27(34)36-3)26(23-18-30-29(38-4)33(23)32-22-15-9-6-10-16-22)25(20(2)31-19)28(35)37-17-11-14-21-12-7-5-8-13-21/h5-10,12-13,15-16,18,26,31-32H,11,14,17H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	3.05	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486779 (CHEMBL2236231) Show SMILES CSc1ncc(C2C(C(=O)OCCCc3ccccc3)=C(C)NC(C)=C2C(=O)OCCCc2ccccc2)n1Nc1ccccc1 |c:25,t:20| Show InChI InChI=1S/C37H40N4O4S/c1-26-32(35(42)44-23-13-19-28-15-7-4-8-16-28)34(31-25-38-37(46-3)41(31)40-30-21-11-6-12-22-30)33(27(2)39-26)36(43)45-24-14-20-29-17-9-5-10-18-29/h4-12,15-18,21-22,25,34,39-40H,13-14,19-20,23-24H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	3.15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486783 (CHEMBL2236210) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1cnc(SC)n1Nc1ccccc1)C(=O)OC(C)C |c:5,10| Show InChI InChI=1S/C24H30N4O4S/c1-7-31-22(29)19-15(4)26-16(5)20(23(30)32-14(2)3)21(19)18-13-25-24(33-6)28(18)27-17-11-9-8-10-12-17/h8-14,21,26-27H,7H2,1-6H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	3.22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Oryctolagus cuniculus)	BDBM50002603 (2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridi...) Show SMILES CCOC(=[OH+])C1=C(C)N=C(C)C(C1c1cccc(c1)[N+]([O-])=O)=C([O-])OCN1C(=O)c2ccccc2S1(=O)=O |w:22.24,c:5,t:8| Show InChI InChI=1S/C25H23N3O9S/c1-4-36-24(30)20-14(2)26-15(3)21(22(20)16-8-7-9-17(12-16)28(32)33)25(31)37-13-27-23(29)18-10-5-6-11-19(18)38(27,34)35/h5-12,22,31H,4,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Alter, S.A. Curated by ChEMBL					Assay Description Blockade of calcium-evoked contractions in depolarized aortic strips				J Med Chem 35: 2407-14 (1992) BindingDB Entry DOI: 10.7270/Q2BV7H7B
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486790 (CHEMBL2236224) Show SMILES COC(=O)C1=C(C)NC(C)=C(C1c1cnc(SC)n1Nc1ccccc1)C(=O)OC |c:4,9| Show InChI InChI=1S/C21H24N4O4S/c1-12-16(19(26)28-3)18(17(13(2)23-12)20(27)29-4)15-11-22-21(30-5)25(15)24-14-9-7-6-8-10-14/h6-11,18,23-24H,1-5H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	3.54	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Oryctolagus cuniculus)	BDBM50002613 (2,6-Dimethyl-4-(2-trifluoromethyl-phenyl)-1,4-dihy...) Show SMILES CC1=NC(C)=C(C(C1C(=O)OCC1CCCCO1)c1ccccc1C(F)(F)F)C(=O)OCN1C(=O)c2ccccc2S1(=O)=O |c:4,t:1| Show InChI InChI=1S/C30H29F3N2O8S/c1-17-24(28(37)42-15-19-9-7-8-14-41-19)26(20-10-3-5-12-22(20)30(31,32)33)25(18(2)34-17)29(38)43-16-35-27(36)21-11-4-6-13-23(21)44(35,39)40/h3-6,10-13,19,24,26H,7-9,14-16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Alter, S.A. Curated by ChEMBL					Assay Description Blockade of calcium-evoked contractions in depolarized aortic strips				J Med Chem 35: 2407-14 (1992) BindingDB Entry DOI: 10.7270/Q2BV7H7B
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Oryctolagus cuniculus)	BDBM50002626 (2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-dihydro-pyridi...) Show SMILES COCCOC(=[OH+])C1=C(C)N=C(C)C(C1c1ccccc1[N+]([O-])=O)=C([O-])OCN1C(=O)c2ccccc2S1(=O)=O |w:24.26,c:7,t:10| Show InChI InChI=1S/C26H25N3O10S/c1-15-21(25(31)38-13-12-37-3)23(17-8-4-6-10-19(17)29(33)34)22(16(2)27-15)26(32)39-14-28-24(30)18-9-5-7-11-20(18)40(28,35)36/h4-11,23,32H,12-14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Alter, S.A. Curated by ChEMBL					Assay Description Blockade of calcium-evoked contractions in depolarized aortic strips				J Med Chem 35: 2407-14 (1992) BindingDB Entry DOI: 10.7270/Q2BV7H7B
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Oryctolagus cuniculus)	BDBM50002607 (4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-p...) Show SMILES COC(=O)C1C(C(C(=O)OCN2C(=O)c3ccccc3S2(=O)=O)=C(C)N=C1C)c1cccc(Cl)c1Cl |c:27,t:24| Show InChI InChI=1S/C24H20Cl2N2O7S/c1-12-18(23(30)34-3)20(15-8-6-9-16(25)21(15)26)19(13(2)27-12)24(31)35-11-28-22(29)14-7-4-5-10-17(14)36(28,32)33/h4-10,18,20H,11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Alter, S.A. Curated by ChEMBL					Assay Description Blockade of calcium-evoked contractions in depolarized aortic strips				J Med Chem 35: 2407-14 (1992) BindingDB Entry DOI: 10.7270/Q2BV7H7B
					More data for this Ligand-Target Pair

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